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Joe Rogan on DMT (Dimethyltryptamine)


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More on DMT

DMT is a powerful psychoactive substance. If DMT is smoked, injected, or orally ingested with an MAOI, it can produce powerful entheogenic experiences including true hallucinations (perceived extensions of reality). A trip sitter is often employed to assist the drug user in staying physically and mentally healthy, and, in the case of smoked DMT, to catch the pipe when the user loses awareness of it.

Smoked: If DMT is smoked, the maximal effects last for a short period of time (5 - 30 minutes +). The onset after inhalation is very fast (less than 45 seconds) and maximal effects are reached within about a minute.

Insufflation: If DMT is insufflated (snorted through the nostrils) it will last slightly longer than if smoked and has less powerful effects.

Injection: Injected DMT produces an experience similar to inhalation in duration, intensity, and characteristics, although by some accounts it is more emotionally clinical (versus spiritual).

DIMETHYLTRYPTAMINE (DMT)
Chemical name 2-(1H-indol-3-yl)-
N,N-dimethylethanamine
Chemical formula C12H16N2
Molar mass 188.27 g/mol
Density 1.099 g/ml
Melting point 49 C and 74 C
(two different crystal structures)
Boiling point 160 C at 0.8 hPa
(reduced pressure)
CAS number 61-50-7
SMILES CN(C)CCC1=CNC2=C1C=CC=C2
Oral ingestion: DMT, which is broken down by the digestive enzyme monoamine oxidase, is inactive if taken orally, unless combined with a monoamine oxidase inhibitor (MAOI). The traditional South American ayahuasca, or yage, is a decocted tea-like mixture containing DMT. There are a number of admixtures to this brew, but most commonly it is simply the leaves of Psychotria viridis (containing DMT), and the vine Banisteriopsis caapi (the MAOI). Other DMT containing plants, including Diplopterys cabrerana, are sometimes used in ayahuasca in different areas of South America. A common source in the western US is Reed canary grass or Phalaris arundinacea, and Harding grass or Phalaris aquatica. This invasive grass contains high levels of DMT and other alkaloids . Taken orally with an appropriate MAOI, DMT produces a long lasting (over 1 hour), slow onset experience. MAOIs should be used with extreme caution as they can have lethal complications with some prescription drugs, such as SSRI antidepressants, and some over-the-counter drugs.

Induced DMT experiences can include profound time-dilation, visual and audio hallucinations, and other experiences that, by most first hand accounts, defy verbal or visual description. Some users report intense erotic imagery and sensations and utilize the drug in a ritual sexual context. Professor Alan Watts described the effects of DMT as "Load universe into cannon. Aim at brain. Fire."

In a 1988 study conducted at UNM, psychiatrist Rick Strassman found that approximately 20% of volunteers injected with high doses of DMT had experiences with a perceived alien entity. At least one subject reported sexual contact with these beings, and many others reported erotic experiences.


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